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The potential role of vascular endothelial growth factor (VEGF) in the faulty bony repair of injured growth plate

University of South Australia
Channel 7 Children's Research Foundation
Dr Rosa Chung

Project Summary

In children, the growth plate is responsible for bone growth; yet its injuries can result in unwanted bony repair causing orthopedic problems requiring invasive corrective surgeries. Currently, little is known of underlying mechanisms for the faulty repair. While VEGF-induced angiogenesis is vital in bone fracture repair, its role is unknown in growth plate bony repair. This study will reveal VEGF's role in growth plate repair, positive information will lead to identification of a potential novel therapeutic target for preventing unwanted bony repair and inducing growth plate regeneration.

Dr Rosa Chung (email)
School of Pharmacy and Medical Sciences
University of South Australia
Business: 830 22716